Article 45 of the 2010 version of GMP stipulates that when necessary, fumigation can be used to reduce microbial contamination in sanitary dead corners in clean areas, and the residual level of fumigants should be verified. In the comments on "Disinfection problems in clean areas" in the "2010 version of GMP FAQs", more and more companies are using hydrogen peroxide vapor disinfection. The sterilization effect can be verified and the residual amount is easy to test.

2023 version of the "GMP Guide": According to the 2023 version of the GMP Guide: HAVC system, it is recommended to regularly or temporarily reduce the microbial load of the production area or HAVC system. Traditional methods cannot perform high-level terminal disinfection on pipelines. Currently, there are pipeline disinfection robots and terminal disinfection technology service manufacturers. Fantong Biological Company disinfects central air-conditioning pipelines in accordance with GMP requirements, using high-level disinfectants. The robot enters the air-conditioning pipeline and uses vaporization technology to seal and disinfect the air-conditioning pipeline, which can kill bacteria and viruses. It is currently the leading technology in China.

Fantong vaporized hydrogen peroxide disinfection, as a disinfection method that meets GMP requirements, is efficient, safe, and residue-free, has gradually become the method of choice for disinfection in more and more pharmaceutical factories. Fantong Bio can formulate targeted disinfection technical plans, arrange corresponding equipment and disinfection processes according to the characteristics of different production functional areas and air-conditioning systems, and completely solve the disinfection problems of clean areas.